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Discovery of Dihydropyrrolo[1,2-a]pyrazin-3(4H)-one-Based Second-Generation GluN2C- and GluN2D-Selective Positive Allosteric Modulators (PAMs) of the N-Methyl-d-Aspartate (NMDA) Receptor., Epplin MP, Mohan A, Harris LD, Zhu Z, Strong KL, Bacsa J, Le P, Menaldino DS, Traynelis SF, Liotta DC., J Med Chem. July 23, 2020; 63 (14): 7569-7600.
Differential Coassembly of α1-GABAARs Associated with Epileptic Encephalopathy., Hannan S, Affandi AHB, Minere M, Jones C, Goh P, Warnes G, Popp B, Trollmann R, Nizetic D, Smart TG., J Neurosci. July 15, 2020; 40 (29): 5518-5530.
Dach1 regulates neural crest migration during embryonic development., Kim YK, Lee H, Ismail T, Kim Y, Lee HS., Biochem Biophys Res Commun. July 5, 2020; 527 (4): 896-901.
Distinct pseudokinase domain conformations underlie divergent activation mechanisms among vertebrate MLKL orthologues., Davies KA, Fitzgibbon C, Young SN, Garnish SE, Yeung W, Coursier D, Birkinshaw RW, Sandow JJ, Lehmann WIL, Liang LY, Lucet IS, Chalmers JD, Patrick WM, Kannan N, Petrie EJ, Czabotar PE, Murphy JM., Nat Commun. June 19, 2020; 11 (1): 3060.
Dynamic properties of noise and Her6 levels are optimized by miR-9, allowing the decoding of the Her6 oscillator., Soto X, Biga V, Kursawe J, Lea R, Doostdar P, Thomas R, Papalopulu N., EMBO J. June 17, 2020; 39 (12): e103558.
DNA methylation dynamics underlie metamorphic gene regulation programs in Xenopus tadpole brain., Kyono Y, Raj S, Sifuentes CJ, Buisine N, Sachs L, Denver RJ., Dev Biol. June 15, 2020; 462 (2): 180-196.
Dynamic heterogeneity and non-Gaussian statistics for ganglioside GM1s and acetylcholine receptors on live cell membrane., He W, Su Y, Peng HB, Tong P., Mol Biol Cell. June 15, 2020; 31 (13): 1380-1391.
Differences in Intrinsic Tubulin Dynamic Properties Contribute to Spindle Length Control in Xenopus Species., Hirst WG, Biswas A, Mahalingan KK, Reber S., Curr Biol. June 8, 2020; 30 (11): 2184-2190.e5.
Desensitization of NMDA channels requires ligand binding to both GluN1 and GluN2 subunits to constrict the pore beside the activation gate., Chen YS, Tu YC, Lai YC, Liu E, Yang YC, Kuo CC., J Neurochem. June 1, 2020; 153 (5): 549-566.
Deorphanization of an odorant receptor revealed new bioactive components for green mirid bug Apolygus lucorum (Hemiptera: Miridae)., Khashaveh A, An X, Shan S, Xiao Y, Wang Q, Wang S, Li Z, Geng T, Gu S, Zhang Y., Pest Manag Sci. May 1, 2020; 76 (5): 1626-1638.
Design and characterization of a novel structural class of Kv1.3 inhibitors., Hendrickx LA, Dobričić V, Toplak Ž, Peigneur S, Mašič LP, Tomašič T, Tytgat J., Bioorg Chem. May 1, 2020; 98 103746.
Divergent Cl- and H+ pathways underlie transport coupling and gating in CLC exchangers and channels., Leisle L, Xu Y, Fortea E, Lee S, Galpin JD, Vien M, Ahern CA, Accardi A, Bernèche S., Elife. April 28, 2020; 9
Determining the correct stoichiometry of Kv2.1/Kv6.4 heterotetramers, functional in multiple stoichiometrical configurations., Möller L, Regnier G, Labro AJ, Blunck R, Snyders DJ., Proc Natl Acad Sci U S A. April 28, 2020; 117 (17): 9365-9376.
De novo variants in SLC12A6 cause sporadic early-onset progressive sensorimotor neuropathy., Park J, Flores BR, Scherer K, Kuepper H, Rossi M, Rupprich K, Rautenberg M, Deininger N, Weichselbaum A, Grimm A, Sturm M, Grasshoff U, Delpire E, Haack TB., J Med Genet. April 1, 2020; 57 (4): 283-288.
Distinct m6A methylome profiles in poly(A) RNA from Xenopus laevis testis and that treated with atrazine., Sai L, Li Y, Zhang Y, Zhang J, Qu B, Guo Q, Han M, Jia Q, Yu G, Li K, Bo C, Zhang Y, Shao H, Peng C., Chemosphere. April 1, 2020; 245 125631.
Direct activation of tRNA methyltransferase-like 1 (Mettl1) gene by thyroid hormone receptor implicates a role in adult intestinal stem cell development and proliferation during Xenopus tropicalis metamorphosis., Na W, Fu L, Luu N, Shi YB., Cell Biosci. March 27, 2020; 10 60.
Distinct functional properties of sodium channel variants are associated with usage of alternative exons in Nilaparvata lugens., Sun H, Du Y, Liu Z, Dong K., Insect Biochem Mol Biol. March 1, 2020; 118 103292.
Dihydropyrimidinase protects from DNA replication stress caused by cytotoxic metabolites., Basbous J, Aze A, Chaloin L, Lebdy R, Hodroj D, Ribeyre C, Larroque M, Shepard C, Kim B, Pruvost A, Moreaux J, Maiorano D, Mechali M, Constantinou A., Nucleic Acids Res. February 28, 2020; 48 (4): 1886-1904.
Dynamics of the nucleosomal histone H3 N-terminal tail revealed by high precision single-molecule FRET., Lehmann K, Felekyan S, Kühnemuth R, Dimura M, Tóth K, Seidel CAM, Langowski J., Nucleic Acids Res. February 20, 2020; 48 (3): 1551-1571.
Dynamic clamp constructed phase diagram for the Hodgkin and Huxley model of excitability., Ori H, Hazan H, Marder E, Marom S., Proc Natl Acad Sci U S A. February 18, 2020; 117 (7): 3575-3582.

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